James Eagan Holmes (born December 13, 1987) is an American convicted on 24 counts of murder and 140 counts of attempted murder for the 2012 Aurora shooting that killed 12 people and injured 70 others at a Century movie theater in Aurora, Colorado, on July 20, 2012. He had no known criminal record prior to the shooting. Holmes booby-trapped his apartment with explosives before the shooting, which were defused one day later by a bomb squad.
Holmes was arrested shortly after the shooting and jailed without bail awaiting trial. Following this, he was hospitalized after attempting suicide several times while in jail. Holmes entered a plea of not guilty by reason of insanity, which was accepted. His trial began on April 27, 2015, and on August 24 he was sentenced to 12 consecutive life sentences plus 3,318 years without parole.
IFS investigated his DNA for defects and generated a CYP450 profile where some significant abnormalities were found.